Controversial End-of-Life Care Bill Amended in California
The bill is designed to improve information and counseling for patients, but it also encourages the use of palliative sedation and voluntary starvation and dehydration, and has been met with strong opposition. <br /> <i>Medscape Medical News</i>

Motesanib Effective in Progressive Differentiated Thyroid Disease
The experimental drug motesanib might be "clinically useful" in progressive differentiated thyroid disease, say researchers reporting a phase 2 trial. <br /> <i>Medscape Medical News</i>

IL-7 Therapy Boosts Immune Response in Cancer Patients
Treatment with recombinant human interleukin-7 was shown to safely induce polyclonal T cell expansion, resulting in dramatic increases in T cell numbers, in patients with refractory cancer <br /> <i>Medscape Medical News</i>

Practical Intervention Addresses Depression in Cancer Patients
Nurses with no previous psychiatric experience can deliver a cost-effective collaborative intervention for cancer patients, researchers show. <br /> <i>Medscape Medical News</i>

Pharmacists Should Participate in Care of Patients With Heart Failure
Dr. George Lundberg talks about why it's important for pharmacists to get involved in the treatment of patients with heart failure. <br /> <i>The Medscape Journal of Medicine</i>

Tarenflurbil Fails to Meet Primary End Point in Phase 3; End of the Road for Development
In a brief statement, Myriad Genetics reports that tarenflurbil failed to have a significant effect in mild AD patients in a phase 3 trial and announced that it will not continue development of the compound. <br /> <i>Medscape Medical News</i>

Household Antibacterial Product Use May Promote Microbial Resistance
A study showed that use of antibacterial products may lead to decreased susceptibility to other antibacterial ingredients and antibiotic resistance in the home. <br /> <i>Medscape Medical News</i>

Multidrug-Resistant Phenotype Linked to Adverse Outcomes in Acinetobacter Infections
Determining resistance phenotypes or genes and their effect on clinical outcomes may help in devising strategies to modify the effect of multidrug-resistant Acinetobacter species on healthcare delivery systems. <br /> <i>Medscape Medical News</i>

Does Transfusion With "Old" Blood Place the Surgical Patient at Risk?
Commentary on a study on duration of stored transfusion blood and surgical outcomes, published March 20, 2008 in The New England Journal of Medicine <br /> <i>Medscape General Surgery</i>

Primary Operative Management vs Medical Management of Pediatric Empyema
A study published in the January, 2008, issue of Archives of Pediatrics and Adolescent Medicine looks at operative vs medical management of pediatric empyema. <br /> <i>Medscape Pediatrics</i>

Unexplained Infertility, Implantation Failure, and Recurrent Spontaneous Abortion: The Role of Thrombophilia and Thyroid Autoimmunity
In this investigation, a high incidence of thrombophilia and thyroid autoimmunity was found in both participants with recurrent miscarriages and repeat implantation failure and controls. <br /> <i>Medscape Ob/Gyn & Women's Health</i>

Primary And Secondary Intra-Abdominal Hypertension-Different Impact on ICU Outcome:. Commentary from F1000
Should you medical and surgical patients be checked for secondary IAH in the ICU? This study was ranked "recommended" and can change clinical practice. <br /> <i>Faculty of 1000 Medicine</i>

Experimental Portable Device Shows Promise in Treating Migraine with Aura
Early treatment with transcranial magnetic stimulation using an experimental, portable handheld device appears to be safe and effective in the treatment of acute migraine with aura. <br /> <i>Medscape Medical News</i>

Novel Cancer Therapy Moving to Human Trials
After experiencing dramatic results with cancer-resistant mice, an investigational new cancer treatment that transfers the naturally occurring cancer-killing activity of granulocytes from a selected donor to a cancer patient is about to begin a phase 2 trial. <br /> <i>Medscape Medical News</i>

Combination Vasopressin and Epinephrine Do Not Improve Cardiac Arrest Outcomes
The lack of superiority of combination therapy vs epinephrine alone suggests it may be futile to add vasopressin to epinephrine during cardiopulmonary resuscitation with advanced cardiac life support. <br /> <i>Medscape Medical News</i>

New AHA Obesity Statement Urges Clinicians to Think Beyond Clinical Treatment and Prevention
Clinicians need to use their influence to advocate for social and environmental change and to help grassroots efforts to help people eat better and be more active in their day-to-day lives. <br /> <i>Medscape Medical News</i>

Synbiotics May Increase a Child's Resistance to Respiratory Tract Infections
In a double-blind, randomized trial, use of probiotics and prebiotics was associated with increased resistance to respiratory tract infections and no apparent adverse events. <br /> <i>Medscape Medical News</i>

FDA Approvals: PrandiMet, Doryx, Doxil
The FDA has approved repaglinide plus metformin HCl tablets (PrandiMet), doxycycline hyclate 150-mg tablets (Doryx), and a new indication for doxorubicin liposome injection (Doxil). <br /> <i>Medscape Medical News</i>

U.S. Leads the World in Illegal Drug Use
A new survey has reported that the United States has the highest level of illegal drug use in the world, with marijuana use widely reported. <br /> <i>WebMD Health News</i>

A 48-Year-Old Man With Penile Trauma and Hematuria
A 48-year-old man suffered a direct blow to his perineum and penis. No damage was initially noted; however, when urinating later, the patient experienced severe pain in his penis and noted a large amount of hematuria. What is the diagnosis? <br /> <i>eMedicine Case Presentations</i>